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April 25, 2025

Developing digital health technologies for frontotemporal degeneration

Frontotemporal degeneration (FTD) is a rare neurodegenerative disease in which patients can present with cognitive, behavioral...

April 3, 2025

Systematic review and consensus conceptual model of meaningful symptoms and functional impacts in early Parkinson’s Disease

A comprehensive, patient-centered conceptual model of early Parkinson’s is lacking and is greatly needed.

March 24, 2025

A Tutorial and Use Case Example of the eXtreme Gradient Boosting (XGBoost) Artificial Intelligence Algorithm for Drug Development Applications

Approaches to artificial intelligence and machine learning (AI/ML) continue to advance in the field of drug development.

March 21, 2025

Wrangling Real-World Data: Optimizing Clinical Research Through Factor Selection with LASSO Regression

Data-driven approaches to clinical research are necessary for understanding and effectively treating infectious diseases.

March 13, 2025

Principles of good practice for translation of electronic clinical outcome assessments

While many publications have outlined good practice recommendations for translation and electronic implementation of clinical...

January 14, 2025

Addressing the need for Standardization of Symptomatic Medication Documentation in Parkinson’s Disease Clinical Research: A Call to Action

People with Parkinson's disease (PD) are prescribed a variety of medications to mitigate symptoms and improve their quality...

February 25, 2025

A Framework to Standardize Gait Study Protocols in Parkinson’s Disease

Research over the past twenty years has shown that gait outcomes have a high sensitivity for diagnosing Parkinson's disease (PD)..

February 1, 2025

Understanding what aspects of Parkinson’s disease matter most to patients and families

Understanding what matters to people with Parkinson’s and their family is essential to derive relevant clinical outcome measures

February 1, 2025

Accelerating Parkinson’s Disease Drug Development with Federated Learning Approaches

Parkinson’s Disease is a progressive neurodegenerative disorder afflicting almost 12 million people...

February 13, 2025

Breaking the silence: challenges and opportunities in pediatric drug development

Pediatric drug development faces signiﬁcant challenges, including underfunding, ethical concerns, and complex regulatory...

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