News & Events
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July 25, 2023
Longitudinal estimated glomerular filtration rate (eGFR) modeling in long-term renal function to inform clinical trial design in kidney transplantation
Authored by: Luke Kosinski, Eric Frey, Amanda Klein, Inish O’Doherty, Klaus Romero, Mark Stegall, Ilkka Helanterä, Ahmed Osama Gaber, William E. Fitzsimmons, Varun Aggarwal, Transplant Therapeutics Consortium (TTC) Abstract Kidney transplantation is the preferred treatment for individuals with end-stage kidney disease. From a modeling perspective, our understanding of kidney function trajectories after transplantation remains limited....... - July 25, 2023
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July 20, 2023
Acute Rejection After Kidney Transplant—An Endpoint Not Predictive of Treatment Effect on Graft Survival
Fitzsimmons, William E. PharmD, MS1,2; Naesens, Maarten MD, PhD3,4... -
July 13, 2023
Diagnostic capacities and treatment practices on implantation mycoses: Results from the 2022 WHO global online survey
Between January and March 2022, WHO conducted a global online survey to collect data on diagnostic capacities and treatment practices in different settings for four implantation mycoses: eumycetoma, actinomycetoma, cutaneous sporotrichosis and chromoblastomycosis. The survey investigated the type of diagnostic methods available in countries at various health system levels (tertiary, secondary, primary level) and the...... -
July 13, 2023
Drug Repurposing for Pandemic Innovation: Establishing an Effective and Efficient Ecosystem
Effective treatments for both existing and emerging diseases may already be available on pharmacy shelves. Many approved drugs have more than one use or benefit but are rarely researched beyond the initial indication for which they are approved. Such research to identify new indications for already-approved drugs is known as drug repurposing. You can read......
