CDRC 2021 Annual Meeting

C-Path’s Cure Drug Repurposing Collaboratory will host a three-day annual meeting in a virtual format, November 16-18, 2021.

Together, with key stakeholder groups including clinicians, researchers, foundations, nonprofits, patient advocates and regulators, CDRC will host a public webinar this November to discuss how the Collaboratory can capture real-world data that generate hypothesis regarding treatment efficacy using repurposed drugs to address diseases of high unmet clinical need. The meeting will include key opinion leaders from numerous disease communities as well as experts on automated EHR data extraction and ways in which these resources can be leveraged to develop partnerships to inform large adaptive platform trials.

What to expect:
Day one will be hosted by the Rare Diseases and Rare Oncology Coordinating Committees. Topics will include:

  • Repurposing case study
  • AI tool predicted ketamine may help ADNP-driven autism
  • The use of repurposed drugs in rare sarcoma subtypes and current examples
  • Patient perspective on drug repurposing for sarcoma
  • Registries for rare tumors and case report forms

Day two will be hosted by the Regulatory, Legislative and Policy working group and the Special Populations Coordinating Committee. Topics will include:

  • Regulatory challenges in drug repurposing
  • U.S. FDA Project Renewal to update drug labels
  • MHRA ILAR Initiative to support alternative regulatory pathways
  • Congenital CMV treatment options and existing guidelines
  • Generating RWD to inform clinical trials
  • Survey tools

Day Three will include sessions dedicated to electronic health record data extraction for COVID-19. Topics will include:

  • Developing registries to leverage RWD from EHRs
  • Data harmonization and common data models
  • International collaboration and data sharing
  • Automating extraction of EHR data

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