Integrated Parkinson’s Database
The database includes integrated and standardized data from both PD observational studies and randomized clinical trials and contains thousands of participants’ data, anonymized and deidentified.
Integrated Parkinson’s Database
The database includes integrated and standardized data from both PD observational studies and randomized clinical trials and contains thousands of participants’ data, anonymized and deidentified. The database covers over 600 variables, such as demographic information, clinical measures, medication usage data, dropouts, and more.
While the database is rich in patient-level outcome measures, it contains limited biomarker and genetics data and does not include any digital health technology data at this time, though we actively strive to acquire additional studies to enrich the database.
We would like to thank our collaborators for their generous contributions to the CPP integrated Parkinson’s Database. View acknowledgements.
Observational Trials Included in the CPP Database
Study Name | Contributor | Participants | Reference | NCT |
Parkinson’s Progression Marker Initiative (PPMI) Biomarker Study | The Michael J. Fox Foundation for Parkinson’s Research | 1563 early PD | Prog Neurobio. 2011 95:629-35 | NCT01141023 |
CamPaIGN | University of Cambridge, UK | 142 early PD | JNNP 2013;84: 1258-1264 | NA |
Tracking Parkinson’s / PRoBaND | University of Glasgow, UK | 1998 early PD | J Park Dis 2015 5:947-59 | NA |
OPDC Discovery Cohort | University of Oxford, UK | 877early PD | J Park Dis 2015 5:269-79 | NA |
PICNICS | University of Cambridge | 280 | J Neurol Neurosurg Psychiatry 2020 Jul;91(7):695-702 | NA |
Randomized Clinical Trials Included in the CPP Database
Study Name | Contributor | Participants | Reference | NCT |
ADAGIO | Teva | 1176 | Lancet Neurol. 2011 May;10(5):415-23 | NCT00256204 |
CONFIDENT-PD (Cogane) | Junaxo & The Michael J. Fox Foundation for Parkinson’s Research | 425 early PD | NCT01060878 | NCT01060878 |
DATATOP | NINDS | 800 early PD | Neurol. 1990;40: 1529-34. | NA |
ELLDOPA | University of Rochester &NINDS | 361 early PD | N Engl J Med 2004; 351:2498-508. | NA |
FS-1 | University of Rochester &NINDS | 200 early PD | Clin Neuropharmacol. 2008; 31(3):141-50 | NCT00063193 |
FS-TOO | University of Rochester &NINDS | 213 early PD | JAMA Neurol. 2014;71(6): 710–716. | NCT00076492 |
Japan Azilect – TVP 1012/CCT-001 | Takeda | 267 | Parkinsonism Related Disord. 2019 Mar; 60:146-152 | NCT02337725 |
Japan Azilect – TVP 1012/CCT-001 – Ext | Takeda | 267 | Parkinsonism Related Disord. 2019 Mar; 60:146-152 | NCT02337725 |
Japan Azilect – TVP-1012 –Phase 2/3 | Takeda | 463 | PLoS One. . 2022 Jan 25;17(1) :e0262796. | NCT02337738 |
Japan Azilect – TVP –Phase 3 | Takeda | 241 | NCT02337764 | NCT02337764 |
NET-PD LS1 | University of Rochester &NINDS | 1741 | JAMA Neurol. 2016 Mar: 73(3): 321-8 | NCT00449865 |
NILO-PD | University of Rochester & Northwestern University | 76 | JAMA Neurol. 2021 Apr; 78(4): 497 | NCT03205488 |
PRECEPT | Teva | 806 | Neurology. 2007 Oct 9;69(15):1480-90 | NCT00040404 |
SP512 | UCB | 273 early PD | Park & Related Disord. 2012 Jun; 18(5):488–93 | NCT00594165 |
SP513 | UCB | 561 early PD | Mov Dis 2007; 22(16):2398–404 | |
SURE PD2 | The Michael J. Fox Foundation for Parkinson’s Research & University of Rochester | 75 | JAMA Neurol. 2014; 71(2):141-50 | NCT00833690 |
SURE PD3 | Massachusetts General Hospital, University of Rochester, NINDS | 298 | JAMA 2021; 326(10):926-939 | NCT02642393 |
STEADY PD3 | University of Rochester & NINDS | 336 | Ann Intern Med. 2020 May 5;172(9):591-598 | NCT0216884 |