April 18 – 20 | 2023 CDRC Annual Meeting
C-Path’s Cure Drug Repurposing Collaboratory will host an in-person, three-day annual Conference and Regulatory Workshop on April 18-20, 2023, at the Hyatt Regency Crystal City in Arlington, Virginia. Together with key stakeholder groups including clinicians, researchers, foundations, nonprofits, patient advocates and regulators, CDRC will host a series of talks and roundtable discussions to share recent accomplishments.
This conference will better define how CDRC can best collaborate to capture real-world data to generate hypothesis regarding treatment efficacy using repurposed drugs for diseases of high unmet clinical need and where there is a lack of commercial incentives. The meeting will include key opinion leaders from numerous disease communities, experts on automated EHR data extraction, regulators from the global community, and partnerships to inform and champion large adaptive platform trials.
CDRC Regulatory Workshop Day 1: Tuesday, April 18
International workshop for publicly funded repurposing programs focusing on projects which do not have a commercial sponsor.
Lunch | 12:00-1:00
Break | 2:30-3:00
Moderators: Marco Schito and David Simon
Next steps (close of open session) | 4:30-45
|April 19 AM||
CDRC Annual Meeting Day 2: Wednesday, April 19
Join via Zoom Meeting: https://c-path-org.zoom.us/j/96887365766?pwd=YkpYUU1XWVpqb1BzZ3hSaFFyQnhwdz09
Development of open-sourced tools to automate the collection of repurposed drugs from electronic medical records to generate real-world data.
Morning: Meeting kickoff on automating data extraction from EHRs
Break | 9:45-10:00
Moderators: Ewy Mathe (NCATS) & Raghav Tirupathi (C-Path)
|April 19 PM||
Lunch | 12:00-1:00
Challenges and opportunities for confirming hypothesis generated by real-world data for repurposed drugs through randomized clinical trials.
Afternoon: Pragmatic adaptive platform trials
Moderators: David Fajgenbaum (U Penn) and Heather Stone (FDA)
Break | 3:15-3:30
Evening: Reception | 6:00-9:00
|April 20 AM||CDRC Annual Meeting Day 3: Thursday April 20
Utility of generating real-world data for assessing repurposed drugs in rare and ultrarare cancers.
Morning: closed door meetings
BREAK | 10:00-10:15 a.m.
LUNCH | 12:00-1:00
|April 20 PM||Afternoon: Rare Cancer (Sarcomas)
Break | 2:45-3:00
Moderator: Marco Schito (C-Path)
Adjourn | 5:00