Critical Path Institute® (C-Path) is pleased to announce that its Disease Modeling Coalition will host a two-day scientific workshop in Paris, France, July 9 – 10, 2026, in collaboration with Institut Imagine.
The workshop will convene regulators, clinicians, researchers, industry experts, and patient representatives to advance innovative evidence-generation approaches for children living with rare and chronic diseases, areas where traditional clinical trial methods are often impractical. Discussions will focus on three priority therapeutic areas: pediatric inflammatory bowel disease, rare epilepsies, and pediatric chronic kidney disease.
The coalition’s work in this space aims to develop disease models and methodologies aligned with international frameworks, including ICH E11A and ICH M15.
In-person participation by invitation is limited to Coalition partners. Remote participation options are available for interested stakeholders. To express interest or learn more, please contact collivier@c-path.org.
About Institut Imagine
Located on the campus of the Hôpital Necker-Enfants malades AP-HP, Institut Imagine is a European leader in research, care, and teaching in the field of genetic diseases. Its unique architecture, designed by Jean Nouvel and Bernard Valéro, brings together 1,000 researchers, doctors, teacher-researchers, engineers, and healthcare staff in a single location, with the aim of accelerating research and diagnostic and therapeutic innovation to change the lives of families affected by genetic diseases. Institut Imagine holds the status of Institut Hospitalo-Universitaire (IHU, awarded in 2011 and 2019) and Institut Carnot (2020), and is supported by six founding members, including AP-HP, Inserm, and Université Paris Cité, as well as private partners and sponsors.
Every day in France, 64 babies are born with a genetic disease. Nearly 8,000 genetic diseases affect more than 3 million people — nearly one in two without a diagnosis, and nearly eight in ten without a dedicated treatment. Faced with this public health emergency, the challenge is twofold: to diagnose and to cure.

