Free Webinar – SOT Clinical and Translational Toxicology Specialty Section (CTTSS): Acetaminophen Induced Liver Toxicity: Mechanisms, Diagnosis and Treatment
Members of C-Path’s Predictive Safety Testing Consortium (PSTC) are among the featured facilitators of a free webinar, sponsored and hosted by the Clinical and Translational Toxicology Specialty Section of the Society of Toxicology, on acetaminophen (APAP) induced liver toxicity.
Join us online Tuesday, Oct. 30, from 1-2 p.m., EST., for a discussion of APAP-induced liver toxicity mechanisms, diagnosis and treatment.
- The webinar will begin with a discussion of the basic mechanisms of APAP-induced hepatocyte cell death in mice and the translational application to human hepatocytes and humans, with the thought that an understanding of these mechanisms may lead to potential new therapeutic targets.
- Next, liquid biopsies and their use in identifying mechanisms of APAP toxicity in humans, and the use of various biomarkers for early diagnosis and prediction of the potential outcome of APAP toxicity and acute liver failure, will be presented.
- Finally, a description of the clinical diagnosis of APAP overdose using protein adduct detection methods and applications, as well as clinical treatment of liver toxicity, will be discussed in order to provide a bench-to-bedside translation of the preclinical data presented.
The webinar will close with a panel discussion to further integrate the information presented and encourage interactive learning.
Registration is required. Click HERE to sign up.